CG-Pra 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with water or other liquids and not chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment for erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks; if treatment is incomplete, take an additional 4 weeks. - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis: 20 mg once daily; if symptoms are not controlled, further consultation is needed.

Children's dosage

Adolescents aged 12 years and older - Gastroesophageal reflux disease (GERD) - Treatment for erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks; if treatment is incomplete, take an additional 4 weeks. - Gastroesophageal reflux disease symptoms without esophagitis.

This medication should not be administered to certain patients. For example, patients allergic to this medication or its ingredients or those who have experienced hypersensitivity should not take it. In addition, patients allergic to penicillin or macrolide antibiotics should exercise caution if taking this medication in combination. Concurrent use with certain heart-related medications or antiviral agents is prohibited. This medication is not recommended for nursing mothers. During treatment, although rare, blood disorders such as leukopenia, thrombocytopenia, hypomagnesemia, hypersensitivity reactions, gastrointestinal symptoms, skin rashes, and various side effects may occur; if any abnormal symptoms arise, consult a doctor immediately. Regular check-ups are needed with long-term use, especially after over a year of continuous use, magnesium levels should be checked periodically. As this medication inhibits gastric acid secretion, there is a slight increased risk of bacterial infections in the gastrointestinal tract, and the risk of fractures may also increase, thus caution is needed for patients at risk of osteoporosis. This medication has many drug interactions, so it is essential to consult healthcare personnel regarding the concurrent use of other medications during treatment with this drug. Although no significant issues were found in animal studies during pregnancy, it should be prescribed cautiously to pregnant women, and breastfeeding mothers should avoid taking it. There is no specific antidote for overdose, so appropriate treatment according to symptoms should be administered, and it should be kept out of reach of children.

Serious side effects

Hives, angioedema, anaphylactic reactions, shock, angioedema, fever, jaundice, hepatitis, liver failure, Stevens-Johnson syndrome (skin and mucous membrane syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, Clostridium difficile-associated diarrhea, myocardial infarction, deep vein thrombosis, QT prolongation, ventricular tachycardia, ventricular fibrillation, Torsades de Pointes.

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, elevated liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, joint pain, muscle pain, muscular weakness, interstitial nephritis, gynecomastia, asthenia, increased sweating, Clostridium difficile-associated diarrhea, abdominal bloating, allergic reactions.

This medication should be stored in a tightly closed container to prevent air or humidity from entering. Additionally, it should be kept at room temperature between 1°C to 30°C, avoiding very cold or hot places.

Appearance

Pink round film-coated tablet

Package unit

28 tablets / PTP [14 tablets / Alu-Alu x 2]