Coftex Tablet (Cetirizine Hydrochloride)

Adult dose

Adults and children over 6 years: Administer 10 mg of cetirizine hydrochloride orally once daily before bedtime. For patients sensitive to side effects, administer 5 mg twice daily, in the morning and evening. Adjust the dosage according to age and symptoms. For patients with renal impairment: The dosing interval should be adjusted according to the patient’s kidney function. Dose adjustment based on creatinine clearance is necessary. - Normal (≥80 mL/min):

Child dose

Adults and children over 12 years: Administer 10 mg of cetirizine hydrochloride orally once daily. Children aged 2 to less than 12: - Weighing 30 kg or more: 10 mg once daily - Weighing less than 30 kg:

This medication should not be taken by individuals who have had allergic reactions to hydroxyzine or piperazine derivatives. Patients with severely impaired kidney function or children under 6 years of age should not use this medication. This drug contains lactose and should not be given to patients with lactose intolerance or specific genetic metabolic disorders. It is advisable to avoid taking this medication together with certain drugs such as theophylline or ritonavir. Taking it with alcohol can exacerbate side effects, so it is best avoided. Patients with weakened kidney or liver function, the elderly, people with epilepsy, pregnant or breastfeeding women should consult a doctor or pharmacist before taking this medication. Elderly patients with diminished kidney function may experience increased drug concentration in the blood, so it is recommended to start at a lower dose and monitor their condition closely. This medication may worsen conditions with poor urine output, so caution is advised for patients with related illnesses. No specific issues were found in animal studies during pregnancy; however, for safety, it is preferable to consult with an expert before taking it. Women who are breastfeeding should be cautious as the drug can be transmitted through breast milk and may affect the baby. Overdosing on this medication can cause symptoms such as confusion, drowsiness, headache, rapid heartbeat, and urinary problems, and immediate consultation with medical personnel is required. During treatment, side effects such as drowsiness, dizziness, indigestion, skin rash, and liver function abnormalities may occur, so any unusual symptoms should be reported to healthcare personnel. It is advisable to stop taking this medication 3-5 days before allergy testing, and caution is needed when driving or operating machinery. Food may slow the absorption rate of this medication, but it does not significantly affect its efficacy.

Serious side effects

• Urticaria, severe swelling (edema), hypersensitivity shock, angioedema, acute generalized exanthematous pustulosis, severe allergic reaction
• Skin reactions that may correspond to serious conditions like high fever with severe rash, blisters, skin peeling, and mucosal pain in the mouth/eyes
• Shortness of breath or difficulty breathing, asthma attacks, respiratory problems accompanied by cough and fever
• Skin or eyes turning yellow (jaundice), extreme lethargy
• Severe neurological symptoms

Mild side effects

• Drowsiness
• headache
• malaise
• numbness
• weakness
• restlessness
• sensory abnormality
• lethargy
• fatigue
• dizziness

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best kept at room temperature, that is, between 1 and 30 degrees Celsius. This ensures the medicine maintains its effectiveness.

Appearance

White rectangular film-coated tablet

Package unit

10 tablets/PTP