Medication info
Siremtal Extended-Release Capsule 200 mg (Cilostazol)

Siremtal Extended-Release Capsule 200 mg (Cilostazol)

Prescription medicationHard capsule경구
Ingredient · strength
Cilostazol›200mg / 1 capsule
Manufacturer / importer
동화약품(주)
Appearance
An upper and lower white hard capsule containing granules that are white or light yellow.
Packaging
Bottle - 30 capsules/bottle, Bottle - 200 capsules/bottle
Approval status
Active

MFDS item code 202001522 · Approved 2020.03.05 · Insurance code 642706780

Summary

Main use
Improvement of chronic arterial occlusion (ulcers, pain) and prevention of recurrent cerebral infarction.
Who takes it
Adults
Adult dose
Cilostazol, usually 200 mg per oral administration once daily for adults. This medication must be taken on an empty stomach, avoiding food.

Ingredients

Manufacturer
동화약품(주)

Efficacy & effects

Improvement of chronic arterial occlusion (ulcers, pain) and prevention of recurrent cerebral infarction.

  • Chronic arterial occlusion
  • Buerger's disease
  • obstructive atherosclerosis
  • diabetic peripheral vascular disease
  • ulcers
  • pain
  • cold sensation
  • cerebral infarction
View approved original text

This medication helps improve ischemic symptoms such as ulcers, pain, and cold sensation caused by chronic arterial occlusion. It also has the effect of preventing recurrence after a cerebral infarction has occurred. Therefore, it is used for the treatment and management of peripheral vascular disease and cerebrovascular disease.

How to take

Adult dose

Cilostazol, usually 200 mg per oral administration once daily for adults. This medication must be taken on an empty stomach, avoiding food.

Precautions

This medication may increase heart rate and can cause symptoms of angina pectoris. Patients should be carefully monitored for angina symptoms. This medication should not be used in patients with a high risk of bleeding, recent hemorrhagic stroke, gastrointestinal bleeding, etc. Patients with symptoms of heart failure should avoid this medication as it may worsen symptoms. Patients who have had allergic reactions to this medication or its ingredients should not use it. Pregnant or potentially pregnant women and nursing mothers should avoid taking this medication. Patients taking anticoagulants, antiplatelet agents, thrombolytics, etc., should use this medication carefully due to an increased risk of bleeding. Women menstruating should also be cautious due to the risk of bleeding. Patients with coronary artery stenosis should be careful as this medication may increase heart rate, worsening angina symptoms. In patients with severe impairment of heart, kidney, or liver function, careful dosing is required as this may increase the concentration of the medication and the risk of side effects. Diabetic patients or patients with uncontrolled hypertension should also be cautious as there is a higher likelihood of side effects such as bleeding when taking this medication. This medication may cause side effects such as headache, diarrhea, palpitations, joint pain, and chest discomfort, and in severe cases may lead to bleeding or heart issues. If any heart irregularities or bleeding symptoms occur, please notify a healthcare provider immediately. Dizziness may occur during administration, so caution should be taken when driving or operating machinery. Taking this medication with food may increase the concentration and risk of side effects, so it is advisable to take it on an empty stomach. It is particularly safe to avoid taking it after a high-fat meal. This medication is primarily metabolized in the liver, so caution should be taken when using it in conjunction with drugs that affect liver metabolism as this may alter the concentration. Pregnant or nursing women should avoid taking this medication as it may affect the fetus or newborn. Safety in children or newborns has not been established, so it is advisable not to use it. Elderly patients may require dose adjustment or careful use due to potential declines in physical function. In cases of overdose, symptoms such as headache, diarrhea, hypotension, and cardiac arrhythmia may occur, and immediate medical assistance should be sought.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, abnormal breathing accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, decreased urine output

Mild side effects

  • Headache
  • diarrhea
  • palpitations
  • joint swelling
  • limb pain
  • chest discomfort
  • rash
  • itching
  • back pain
  • infection
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  • chills
  • malaise
  • neck stiffness
  • pelvic pain
  • retroperitoneal hemorrhage
  • palpitations
  • tachycardia
  • flushing
  • increased blood pressure
  • anxiety
  • dizziness
  • drowsiness
  • tremors
  • abnormal stools
  • dyspepsia
  • cholelithiasis
  • colitis
  • esophagitis
  • gastritis
  • gastroenteritis
  • gum bleeding
  • melena
  • abdominal pain
  • nausea
  • vomiting
  • loss of appetite
  • heartburn
  • abdominal distension
  • hematuria

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius. Proper storage will help maintain the medication’s effectiveness for a longer time.

Appearance and packaging

Appearance

An upper and lower white hard capsule containing granules that are white or light yellow.

Package unit

Bottle - 30 capsules/bottle, Bottle - 200 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.