Hyden Plus Tablet 160/12.5 mg

Adult dose

The recommended adult dosage is 1 tablet containing Valsartan 80 mg/Hydrochlorothiazide 12.5 mg taken once daily with a small amount of water, regardless of meals. The dosage of Valsartan 160 mg/Hydrochlorothiazide 12.5 mg is applicable if prescribed for blood pressure reduction. The maximum effect of blood pressure reduction appears after 2 to 4 weeks. No dosage adjustment is needed for patients with renal impairment (creatinine clearance greater than 30 mL/min).

This medication can cause serious harm to the fetus, especially during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be used in patients with allergies to specific components or severe liver dysfunction, and patients with significantly reduced kidney function. It should be used with caution in cases of electrolyte imbalance such as hypokalemia, hyponatremia, or hypercalcemia, especially in patients with poor kidney or liver function, elderly patients, and patients with heart disease. Patients may experience dizziness or drowsiness while taking this medication, so caution is needed when driving or operating machinery. Do not take potassium supplements or potassium-containing medications without consulting a physician. This medication lowers blood pressure, so if symptoms of hypotension occur, consult a physician immediately. Be cautious as blood pressure may drop sharply due to dehydration or excessive sweating. It is important to regularly monitor electrolyte levels and kidney function during treatment to ensure there are no abnormalities. This medication may interact with other antihypertensives, diuretics, lithium preparations, non-steroidal anti-inflammatory drugs, etc., so it is essential to inform the physician of any other medications being taken. Hydrochlorothiazide may cause sensitivity to sunlight, so caution should be exercised regarding UV protection and skin care during treatment. In cases of overdose, serious side effects such as hypotension, arrhythmias, and electrolyte abnormalities may occur, requiring immediate medical attention. Safety and efficacy have not been established in children, and although no special dosage adjustment is needed for the elderly compared to normal adults, care should be taken for side effects. This medication should be stored away from moisture and direct sunlight, and out of reach of children.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme drowsiness, sudden and severe headache, thunderclap headache, seizure, altered consciousness, visual disturbances, paralysis,

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• fatigue
• back pain
• cough
• upper respiratory infection
• diarrhea
• arthralgia
• abdominal pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture and kept in a cool place below 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication for a longer period.

Appearance

Dark red oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle