Medication info
Rpicifloxacin Tablets 250 mg (ciprofloxacin hydrochloride monohydrate)

Rpicifloxacin Tablets 250 mg (ciprofloxacin hydrochloride monohydrate)

Prescription medicationTablet경구
Ingredient · strength
Ciprofloxacin Hydrochloride Hydrate›291mg / 1 tablet
Manufacturer / importer
(주)알피바이오
Appearance
white round film-coated tablets
Packaging
For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle
Approval status
Active

MFDS item code 201907281 · Approved 2019.10.16 · Insurance code 661605130

Summary

Main use
Treatment of various bacterial infections including respiratory infections and urinary tract infections
Who takes it
Adults
Adult dose
For typical adult dosing of ciprofloxacin, take 250 to 500 mg orally twice daily during meals. For severe complicated infections, the dosage may be increased to 750 mg twice a day. In cases of acute infections, treatment usually lasts 5 to 10 days, and it should be administered for at least 3 additional days after symptoms have resolved. Dosing and intervals should be adjusted for patients with renal impairment based on creatinine clearance. Adjust as appropriate according to symptoms.

Ingredients

Manufacturer
(주)알피바이오

Efficacy & effects

Treatment of various bacterial infections including respiratory infections and urinary tract infections

  • Respiratory infections excluding acute bronchitis
  • community-acquired pneumonia
  • pharyngitis
  • tonsillitis
  • laryngitis
  • external otitis
  • chronic cholesteatomatous otitis media
  • chronic otitis media
  • bacterial prostatitis
  • acute uncomplicated cystitis
  • acute pyelonephritis
  • complicated urinary tract infections
View approved original text

This medication is used for the treatment of various infections caused by different bacteria. It is effective for respiratory infections excluding acute bronchitis and community-acquired pneumonia, as well as infections of the ears, nose, and throat. Additionally, it treats urogenital infections such as bacterial prostatitis, acute uncomplicated cystitis, acute pyelonephritis, and complicated urinary tract infections. It is also used for gonococcal cervicitis and urethritis, gastrointestinal infections, bile duct infections, skin and soft tissue infections, bone and joint infections, gynecological infections, peritonitis, and infections around the eyes. However, due to the characteristics of fluoroquinolone antibiotics, it is restricted to limited use in certain mild infections when alternative treatments are not available. This medication is used for the treatment of various infections as mentioned above.

How to take

Adult dose

For typical adult dosing of ciprofloxacin, take 250 to 500 mg orally twice daily during meals. For severe complicated infections, the dosage may be increased to 750 mg twice a day. In cases of acute infections, treatment usually lasts 5 to 10 days, and it should be administered for at least 3 additional days after symptoms have resolved. Dosing and intervals should be adjusted for patients with renal impairment based on creatinine clearance. Adjust as appropriate according to symptoms.

Precautions

This medication is a fluoroquinolone antibiotic used for the treatment of specific bacterial infections. However, it can cause serious side effects such as tendonitis or tendon rupture, peripheral neuropathy, and central nervous system abnormalities. Particularly, patients with myasthenia gravis are at risk of exacerbating symptoms and should not use this medication. If pain or inflammation occurs in the tendons during the course of treatment, use should be stopped immediately, and a physician should be consulted, and exercise should be avoided during such symptoms. Additionally, it should not be used in pregnant or breastfeeding women, children under 18 years old, patients with epilepsy, or patients who have previously had allergic reactions to this or similar drugs. This medication should be used cautiously in patients with severe renal impairment, older adults, and patients with central nervous system disorders, as the risk of side effects may increase when combined with certain other medications, so consultation with a physician or pharmacist is necessary. If symptoms such as seizures, changes in mental status, severe diarrhea, skin rashes, visual disturbances, or breathing difficulties occur during the use of this medication, it should be stopped immediately, and healthcare professionals should be informed. Moreover, it can affect blood glucose control, so diabetic patients should carefully monitor their blood sugar levels, and it has many drug interactions, so any medications being taken should be disclosed. This medication may respond sensitively to sunlight, so strong sun exposure should be avoided, and use should be discontinued if side effects are suspected. Lastly, this medication must only be taken for the appropriate duration as per a doctor's prescription and instructions, and it is important to consult healthcare professionals immediately if any unusual symptoms occur during treatment.

Side effects and when to seek care immediately

Serious side effects

tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic reactions, anaphylactic shock, serum sickness-like reactions, bone marrow suppression, liver dysfunction, jaundice, hepatitis, cholestatic jaundice, hepatic necrosis, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), seizures, status epilepticus, confusion, suicidal thoughts and behavior, acute generalized exanthematous pustulosis

Mild side effects

fungal superinfection, thrombocytopenia, syndrome of inappropriate antidiuretic hormone secretion (SIADH), allergic reactions, allergic swelling/angioedema, loss of appetite, increase in alkaline phosphatase levels, hyperglycemia, hypoglycemia, psychomotor agitation/restlessness, confusion, disorientation, emotional instability, abnormal dreams, depression, hallucinations, psychiatric reactions, toxic psychosis, headache, dizziness, sleep disorders, taste disorders, insomnia, sensory disturbances, sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, at a safe temperature between 1 to 30 degrees Celsius. Therefore, avoid storing it in excessively hot or excessively cold places, and keep it in an area with appropriate temperature control.

Appearance and packaging

Appearance

white round film-coated tablets

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.