Medication info

Hiroxacin Tablet 500 mg (Levofloxacin Hydrate)

Prescription medicationTablet경구Expired
Ingredient · strength
Levofloxacin Hydrate›512.3mg / 1 tablet
Manufacturer / importer
(주)휴비스트제약
Appearance
Pink rectangular film-coated tablets
Packaging
For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle
Approval status
Expired

MFDS item code 201905381 · Approved 2019.07.30

This product's status changed to Expired on 2024.07.30. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.
Who takes it
Adults
Adult dose
For adults, Levofloxacin is administered orally once daily at 250-750 mg. For patients with normal kidney function, depending on the type of infection, doses range from 250 mg to 750 mg every 24 hours, with treatment durations varying from 3 days to 28 days. In patients with renal impairment, the dosage is adjusted according to creatinine clearance, and the dosage and administration intervals are modified to every 24 or 48 hours. For blood and peritoneal dialysis

Ingredients

Manufacturer
(주)휴비스트제약

Efficacy & effects

Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary infections
  • uncomplicated urinary infections
View approved original text

This drug is used to treat infections caused by various bacteria. The main indications include complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, chronic bacterial prostatitis, and acute pyelonephritis, among others. As a fluoroquinolone derivative, there is a possibility of serious adverse reactions, and it should be used in cases where other treatment options are not available for acute bacterial sinusitis, acute exacerbation of chronic bronchitis, uncomplicated urinary infections, and complicated skin and soft tissue infections. This drug is effective against various bacteria such as Streptococcus pneumoniae, Staphylococcus aureus, and Escherichia coli, helping with infection treatment. Patients must take this medication as directed by their physician and should consult immediately if adverse reactions occur. This drug is used to improve symptoms of infection and treat infections.

How to take

Adult dose

For adults, Levofloxacin is administered orally once daily at 250-750 mg. For patients with normal kidney function, depending on the type of infection, doses range from 250 mg to 750 mg every 24 hours, with treatment durations varying from 3 days to 28 days. In patients with renal impairment, the dosage is adjusted according to creatinine clearance, and the dosage and administration intervals are modified to every 24 or 48 hours. For blood and peritoneal dialysis

Precautions

This drug belongs to a specific type of antibiotics and may cause serious problems with tendons such as tendonitis or tendon rupture. If such symptoms occur, it should be discontinued immediately, and it should not be used in patients with myasthenia gravis as it may worsen their symptoms. Additionally, this drug can affect the nervous system, causing dizziness, seizures, and psychiatric symptoms, requiring caution. Those with epilepsy or brain conditions should be especially careful. It is safe to avoid use in children under 18 years of age, pregnant women, and breastfeeding women. Also, patients with liver disease or a history of certain allergies should avoid taking it. Elderly patients or those with poor kidney function may experience delayed excretion of the drug, necessitating dosage adjustment and careful monitoring. Diabetic patients should monitor their blood glucose levels closely, as changes may occur. During treatment with this drug, care should be taken to avoid strong sunlight or artificial UV exposure, and if skin rashes or hypersensitivity reactions occur, it should be discontinued immediately. There may be dizziness or drowsiness while driving or operating machinery, so caution is needed. This drug can interact with other medications, especially antacids, iron supplements, calcium supplements, hypoglycemic agents, and anticoagulants, so consultation with a physician or pharmacist is recommended when taking them together. In case of overdose, cardiac rhythm disturbances or central nervous system symptoms may occur, requiring immediate medical attention. This drug should be used only for the minimum duration necessary for treatment, and it is vital to alert healthcare personnel immediately if any abnormal symptoms occur.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in the oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headaches, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Nausea
  • diarrhea
  • vaginitis
  • insomnia
  • abdominal pain
  • bloating
  • itching
  • dizziness
  • rash
  • indigestion
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  • stomatitis
  • glossitis
  • dryness of the mouth
  • constipation
  • vomiting
  • fungal infections
  • genital itching
  • headache
  • neurosis
  • erythematous rash
  • urticaria
  • decreased appetite
  • drowsiness
  • excitement
  • thirst
  • tremors
  • allergic reactions
  • palpitations
  • QT interval prolongation
  • arrhythmia
  • increased BUN and serum creatinine
  • elevated liver enzyme levels
  • ALP
  • γ-GTP

Not everyone experiences these, and they can vary from person to person.

Storage

This drug may be sensitive to air and moisture; therefore, it should be stored in a tightly closed container. The recommended storage temperature is to maintain room temperature between 1 degree to 30 degrees Celsius. Doing so will help preserve the drug's effectiveness and safety over time.

Appearance and packaging

Appearance

Pink rectangular film-coated tablets

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.