Ezetimibe Tablet (Ezetimibe)

Adult dosage

The recommended dose of this drug is 10 mg once daily, administered without regard to meals. When taken in combination with HMG-CoA reductase inhibitors, start administration of this drug at the recommended initial dose of the HMG-CoA reductase inhibitor, and if already receiving a high dose of the HMG-CoA reductase inhibitor, continue maintaining the dose of the HMG-CoA reductase inhibitor while taking this drug. Fenofibrate should be considered as part of the management.

This drug should not be used in patients who are allergic to specific components. Patients with active liver disease or persistently elevated liver enzyme levels should not take this drug along with specific lipid-lowering agents. Caution is required for pregnant or nursing women, as the use of this drug with certain lipid-lowering agents is prohibited. Patients with moderate to severe liver impairment should avoid using this drug and should undergo regular liver function tests. If symptoms such as myalgia or muscle weakness occur, the physician should be informed immediately, and care must be taken for muscle-related adverse reactions. Patients with impaired kidney function should also be cautious when taking this drug, and dosage adjustment or monitoring may be necessary. Drug interactions may occur when combined with other medications, especially anticoagulants, immunosuppressants, and lipid-lowering agents. The use of this drug in special populations such as children, the elderly, pregnant women, and nursing mothers should be restricted or carefully considered. In the case of overdose, there is no specific treatment, so immediate consultation with medical personnel is crucial, and general supportive therapy is essential. This drug should be stored out of reach of children, and changing containers should be avoided.

Serious side effects

Hives, severe swelling (edema), mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), hypersensitivity reactions including rash and angioedema, severe allergic reactions, severe rash with high fever, blisters, exfoliative skin reactions, severe skin reactions including oral/ocular mucosal pain, drug reaction with eosinophilia and systemic symptoms (DRESS), severe skin abnormalities including erythema multiforme

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infection
• pharyngitis
• sinusitis
• arthralgia
• low back pain
• cough
• dizziness

Store this drug in a tightly closed container to protect it from exposure to air and moisture. Additionally, the medication should be kept at room temperature between 1°C and 30°C, avoiding very hot or very cold environments.

Appearance

White to almost white oblong tablets

Package unit

30 tablets/box [(10 tablets/PTP*3)]