Mega Atova Tablet 20mg (Atorvastatin Calcium Hydrate)

Adult dosage

Atorvastatin is administered once daily at doses ranging from 10 mg to 80 mg, regardless of food intake at any time of the day. The initial dose is 10 mg once daily, but for patients requiring a greater reduction in LDL cholesterol, it may be started at 20 mg or 40 mg once daily. Lipid levels should be analyzed within 2 to 4 weeks after starting treatment, and doses should be adjusted accordingly. For patients with homozygous familial hypercholesterolemia, the dosing range is 10 mg to 80 mg once daily, in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) when applicable or when such treatments are not available. For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17), the recommended initial dose is 10 mg once daily, with a maximum recommended dose of 20 mg per day (there is no clinical data for doses higher than 20 mg in pediatric patients). The dosage should be adjusted according to individual treatment goals. Adjustments should be made every 4 weeks or more. ○ In patients with renal impairment: Kidney disease does not affect atorvastatin plasma concentration or LDL cholesterol-lowering efficacy; thus, dose adjustments are not necessary. ○ In the elderly: The efficacy and safety for patients aged 70 and older are similar to that of the general adult population.

Children's dosage

For pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia, a recommended initial dose is 10 mg once daily, with a maximum dose of 20 mg per day. Dosage should be adjusted based on treatment responses every 4 weeks or longer.

This medication may pose a risk of muscle problems; thus, if muscle pain or weakness worsens or if creatine kinase levels rise significantly, stop taking the medication immediately and consult a physician. Individuals with poor liver function or liver disease should not take this medication, and if symptoms of liver dysfunction occur during treatment, they should inform a doctor immediately. Women who are pregnant, may become pregnant, or breastfeeding should not take this medication, and women of childbearing age should use appropriate contraceptive methods while taking it. Children under 10 years of age and patients with muscle disorders should also avoid this medication. Patients with a history of alcohol addiction or liver disease should use this medication cautiously, and elderly patients aged 70 or older are at higher risk of muscle-related side effects and should be monitored closely. This medication can interact with other drugs, so it is essential to inform your physician or pharmacist, especially if you are taking certain antibiotics, antifungals, protease inhibitors, or some cardiovascular drugs. Be cautious if taking this medication with grapefruit juice or certain other drugs, as it may increase the blood concentration of the medication and heighten the risk of side effects. If symptoms such as muscle pain, weakness, fever, or fatigue develop while taking this medication, notify a doctor immediately and get tested, and discontinue use if necessary. Regular monitoring of liver function tests and blood creatine kinase levels is necessary, and immediate action should be taken if abnormalities are found. Store this medication out of reach of children, and keep it in its original container. There is no specific antidote for overdose; treatment should be symptom-based, while closely monitoring liver function and muscle condition.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty in breathing, asthma attacks, respiratory problems with cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, liver disorders (jaundice), sudden and

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best kept at room temperature between 1 to 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle