Sambica HCT Tablet 5/40/12.5mg

Adult dose

This medication is taken once daily, with or without food, with water. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosages are as follows: - 5/20/12.5mg: For patients whose blood pressure is not adequately controlled with the combination of amlodipine/olmesartan medoxomil 5/20mg. - 5/40/12.5mg: For patients with blood pressure not adequately controlled with amlodipine/olmesartan medoxomil 5/40mg.

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years of age have not been established; therefore, its use is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; hence, it should be discontinued immediately upon confirmation of pregnancy. Do not take this medication if you are allergic to any of its components or similar drugs, are pregnant or lactating, or have severe hypotension, valvular heart disease, acute heart failure, or severe renal or hepatic disease. Patients with low blood volume or electrolyte imbalance should be closely monitored initially, as blood pressure may drop sharply upon administration; immediate action should be taken if hypotensive symptoms occur. This medication may affect kidney function, so patients with weakened kidney function should regularly check their kidney status and electrolyte levels through blood tests. Patients with impaired liver function or progressive liver cirrhosis may experience severe side effects, such as hepatic coma, when using this medication; caution is required. As this medication has blood pressure-lowering effects, elderly patients or those with other cardiovascular conditions should use it with particular caution and monitor to avoid excessive hypotension. While taking this medication, dizziness or drowsiness may occur; thus, it's advisable to avoid risky activities such as driving or operating machinery. This medication can interact with other drugs, so particularly when taken with lithium, non-steroidal anti-inflammatory drugs, other antihypertensives, and potassium-sparing diuretics, consult a physician. If photosensitivity reactions appear on the skin or new skin lesions develop, inform a doctor immediately, limit sun exposure, and take appropriate protective measures. This medication is not recommended for use in children, as its safety and efficacy have not been established. In case of overdose, symptoms such as hypotension and palpitations may occur; seek medical attention promptly for appropriate treatment. Store in a place out of reach of children, avoiding moisture, heat, and direct sunlight.

Serious side effects

• Urticaria, angioedema, Quincke's edema → severe allergic reaction
• Severe rash, blisters, skin peeling, pain in oral/ocular mucosa accompanied by high fever → severe skin reaction
• Respiratory difficulties, acute respiratory distress syndrome (ARDS), pulmonary edema → respiratory issues
• Jaundice (cholestatic jaundice) → liver abnormality (jaundice)
• Pre-syncope, seizures, myocardial infarction, arrhythmias (including bradycardia, ventricular tachycardia, and atrial fibrillation), thrombosis, embolism, paralysis.

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory infection
• nasopharyngitis
• urinary tract infection
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication should be stored in a sealed container that prevents air or moisture from entering. Additionally, it is best to keep the medication at room temperature between 1°C and 30°C.

Appearance

Pale yellow round film-coated tablets

Package unit

30 tablets (10 tablets/Alu-Alu x 3)