Lowbica HCT Tablets 5/20/12.5 mg

Adult dose

This medication is taken once daily with water, regardless of meals. It is advised to take it at the same time every day (e.g., in the morning). The maximum dosage is amlodipine/olmesartan medoxomil/hydrochlorothiazide of 10/40/25 mg. The maximum antihypertensive effect occurs within two weeks after administration, so dosages should be adjusted with intervals of more than two weeks based on blood pressure response. The recommended dosages are as follows:

Child dose

Safety and efficacy for pediatric patients under 18 years have not been established; therefore, use of this medication is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. It should not be used in patients with allergies to any of its ingredients or similar medications, those who are pregnant or breastfeeding, patients with severe hypotension, heart disease, or severe kidney or liver dysfunction. Patients with low blood volume or salt depletion may experience hypotension; therefore, their condition should be carefully monitored and appropriate measures taken if necessary before starting treatment. Patients with impaired kidney function or kidney transplant recipients should have their electrolyte levels and kidney function tested regularly, and patients with narrowed renal arteries should also be cautious. Patients with liver disease or impaired liver function, as well as those with heart valve disease, also require special caution when using this medication. Since this medication lowers blood pressure, there is a risk of dizziness when driving or operating hazardous machinery. During treatment, the skin may become sensitive to sunlight; therefore, sun exposure should be avoided and appropriate protection should be used if necessary. Caution is advised when taking this medication concurrently with lithium, nonsteroidal anti-inflammatory drugs (NSAIDs), and other drugs, as this may increase the risk of side effects. The effects may be enhanced when this medication is used with other antihypertensive agents; thus, it must be taken under the direction of a physician. This medication has not been established as safe and effective for children, so it is not recommended for them. Elderly patients may react more sensitively to this medication, so it is recommended to start with a lower dose and adjust it cautiously. In the event of overdose, severe hypotension and heart rhythm disturbances may occur, requiring immediate medical treatment and possibly treatment to raise blood pressure. This medication should be stored in a cool, dry place, away from moisture and heat, and out of reach of children.

Serious side effects

Hives, severe swelling (edema), anaphylactic reaction, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, Stevens-Johnson syndrome, difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, shortness of breath or difficulty breathing, yellowing of the skin or eyes (jaundice), extreme fatigue, jaundice, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory tract infection
• nasopharyngitis
• urinary tract infection
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication must be kept in a tightly sealed container to avoid exposure to air or moisture. The recommended storage temperature is at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy and safety.

Appearance

White-orange round film-coated tablets

Package unit

28 tablets (14 tablets/PTP X 2)/box