Medication info

Cough Relief ES Syrup

OTC medicationSyrup경구
Ingredient · strength
Dextromethorphan Hydrobromide Hydrate›75mg / 100mLDL-Methylephedrine Hydrochloride›131.25mg / 100mLChlorpheniramine Maleate›15mg / 100mLAmmonium Chloride›1g / 100mL
Manufacturer / importer
지엘파마(주)
Appearance
A light reddish-brown syrup
Packaging
20mL/box x 20, 20mL/box x 6
Approval status
Active

MFDS item code 201900312 · Notified 2019.01.22

Summary

Main use
Relief of cough and phlegm
Who takes it
Adults · Children
Adult dose
20 mL per dose, taken 3 to 4 times a day after meals and before bedtime.
Child dose
Ages 11 to less than 15: 13 mL per dose. Ages 8 to less than 11: 10 mL per dose. Ages 5 to less than 8: 7 mL per dose. Ages 3 to less than 5: 5 mL per dose. Ages 2 and older:

Ingredients

Manufacturer
지엘파마(주)

Efficacy & effects

Relief of cough and phlegm

  • Cough
  • phlegm
View approved original text

This medication is primarily used to relieve symptoms of cough and phlegm.

How to take

Adult dose

20 mL per dose, taken 3 to 4 times a day after meals and before bedtime.

Child dose

Ages 11 to less than 15: 13 mL per dose. Ages 8 to less than 11: 10 mL per dose. Ages 5 to less than 8: 7 mL per dose. Ages 3 to less than 5: 5 mL per dose. Ages 2 and older:

Precautions

This medication should not be taken by individuals who are allergic to it or have previously experienced hypersensitivity reactions to its components. Furthermore, those taking specific medications such as antidepressants or antipsychotics, or who have recently discontinued such medications within the last two weeks, should not use this medication. Infants under 3 months old or children under 15 years old should avoid taking this medication, depending on the type. During the use of this medication, do not take other cough medicines, cold remedies, allergy medications, sedatives, or alcohol. It is advisable not to drink alcohol during treatment and to avoid driving or operating machinery as drowsiness may occur. Individuals under 2 years old, those with allergic tendencies, liver, kidney, or thyroid diseases, those with heart conditions or hypertension, and women who are pregnant or breastfeeding should consult a healthcare professional before use. Caution is also advised for individuals with glaucoma or urinary disorders. If a cough persists for a long time or is severe, or if symptoms such as fever or rash accompany it, stop taking this medication and seek advice from a professional. If any abnormal symptoms such as rash, itching, vomiting, or dizziness occur after taking the medication, discontinue use immediately and consult a professional. This medication must be used according to the prescribed dosages and methods, and when given to children, should be managed by a guardian. Store in a place out of reach of children, avoid direct sunlight, and keep in a cool, dry place. Also, do not transfer the medication to other containers to prevent misuse and to maintain drug quality.

Side effects and when to seek care immediately

Serious side effects

Hives

Mild side effects

  • Rash
  • redness
  • itching
  • nausea
  • vomiting
  • loss of appetite
  • dizziness
  • anxiety
  • tremors
  • insomnia
Show 2 more
  • difficulty urinating
  • excessive or severe thirst

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

Do not take this medication with MAO inhibitors (antidepressants, antipsychotic medications, mood stabilizers, Parkinson's disease medications, etc.), other cough expectorants, cold medications, antihistamines, or sedatives.

Food interactions

Do not consume alcohol while taking this medication.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. Avoid excessively hot or cold environments, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

A light reddish-brown syrup

Package unit

20mL/box x 20, 20mL/box x 6

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QAfter taking it, my hands are trembling and I feel anxious.

    Tremors, anxiety, and insomnia are noted as adverse reactions associated with this medication. If these symptoms occur, stop taking it immediately and consult a doctor or pharmacist.

    Answers 1 · 2026.09.14

  • QIs it okay to give before bedtime?

    It is recommended to take the medication 3-4 times a day after meals and at bedtime, which includes taking it before sleep. Adhere to the appropriate dosage by age, and consult a doctor if under 2 years old.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.