Olmesartan Medoxomil/Amlodipine Besylate/Hydrochlorothiazide Tablet 10/40/12.5 mg

Adult dose

This medication should be taken once daily with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dose is as follows. - 5/20/12.5mg: administered to patients whose blood pressure is not adequately controlled with the combination therapy of amlodipine/olmesartan medoxomil 5/20mg. - 5/40/12.5mg: administered to patients whose blood pressure is not adequately controlled with the combination therapy of amlodipine/olmesartan medoxomil 5/40.

Child dose

The safety and efficacy in pediatric patients under 18 years of age have not been established; therefore, the administration of this medication is not recommended.

This medication can cause serious harm to the fetus and newborn during the second and third trimesters of pregnancy, therefore use should be stopped immediately upon confirmation of pregnancy. Do not use in patients with allergies to this medication or its components, those with specific heart, kidney, or liver diseases, and women who are pregnant or breastfeeding. Caution is needed for patients with very low blood pressure or acute heart problems, severe kidney or liver dysfunction as use of this medication can be dangerous. Patients with reduced blood volume or dependent kidney function may experience hypotension or worsening kidney function, requiring careful monitoring at the start of treatment. This medication can cause electrolyte imbalances, hence regular blood tests are necessary to check levels of potassium, sodium, etc. While taking this medication, dizziness or lightheadedness may occur, so it is advisable to avoid driving or operating hazardous machinery. This medication may interact with other drugs, particularly lithium, some pain relievers, and other blood pressure medications, so consultation with a doctor is necessary when taking such medications together. This medication can be used in the elderly, but dosage adjustments may be necessary due to differences in drug effectiveness owing to diminished liver or kidney function. Overdose may result in symptoms such as hypotension and palpitations, so it is crucial to adhere to the prescribed dosage and inform healthcare personnel of any abnormal symptoms. This medication should be stored away from moisture and heat, avoid direct sunlight, and out of reach of children, and it is advisable not to transfer it to another container.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanying cough+fever, yellowing of skin/eyes (jaundice), extreme drowsiness, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory tract infection
• rhinitis
• urinary tract infection
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is best to store it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

Grayish-red round film-coated tablets

Package unit

30 tablets (10 tablets/Alu-Alu × 3)