Simpex Duo Tablet 10/10mg

Adult dose

This medication is administered once daily in the evening, regardless of meals. The dose range for patients with primary hypercholesterolemia is 10/10mg to 10/40mg per day, with a commonly recommended starting dose of 10/20mg per day. Patients with less need for LDL cholesterol reduction may start with 10/10mg per day. After starting this treatment or adjusting the dose, blood lipid levels should be checked at least 4 weeks later before making any dose adjustments.

This medication is used to lower cholesterol. Caution should be exercised as muscle problems may occur when taking this medication. If muscle pain or weakness occurs, inform a doctor immediately. The risk of muscle damage may increase, especially when taking high doses or in conjunction with certain other drugs. This medication may affect liver function; therefore, it should not be used in patients with liver disease or elevated liver enzymes. Women who are pregnant or breastfeeding must not use this medication, and women of childbearing potential should only take it after confirming the possibility of pregnancy. This medication may interact with specific drugs; if taking other medications, always inform your doctor or pharmacist. It is not recommended for children or patients under 10 years old, and caution is required when given to the elderly. If any unusual symptoms occur while taking this medication, consult healthcare professionals immediately, and regular blood tests to monitor liver and muscle status are advisable. There is no specific antidote for overdose; therefore, you will receive general treatment according to the symptoms. It is advisable to avoid certain foods, such as grapefruit juice, while taking this medication.

Serious side effects

Hives, angioedema, rash, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, severe skin reactions, hepatitis, liver abnormalities (including jaundice), liver failure, cholecystitis, pancreatitis, severe edema, severe allergic reactions, severe skin reactions, severe symptoms related to cardiovascular disease, rhabdomyolysis, myopathy, increased creatine kinase (CK), severe

Mild side effects

Headache, diarrhea, influenza, upper respiratory infection, muscle pain, limb pain, fatigue, nausea, abdominal pain, constipation, vomiting, itching, dizziness, paraesthesia, insomnia, weakness, increased serum creatine phosphokinase (CPK), weight loss, nocturia, hematuria, epigastric pain, sore throat

This medication is sensitive to air and moisture and should be stored in a tightly sealed container. Additionally, it is important to maintain its effectiveness by storing it at room temperature between 1°C and 30°C.

Appearance

White to pale yellow, bilaterally convex rectangular tablet

Package unit

30 tablets (10 tablets/PTP × 3)