Duo-rovand Tablet 10/5 mg (Ezetimibe (Micronized), Rosuvastatin Calcium)

Adult dose

This medication is administered once daily, regardless of meals. The recommended initial dosage is 10/5mg per day. In patients requiring a greater reduction in LDL cholesterol, the dosage can be adjusted. After appropriate dosing, blood lipid levels should be checked at intervals of more than 4 weeks, and the dosage can be adjusted accordingly, with a maximum increase of up to 10/20mg per day.

This medication has a rare side effect that may cause serious problems with muscles, so if you experience severe muscle pain or muscle weakness, you should inform your doctor immediately. Patients with serious infections, hypotension, major surgery or trauma, or metabolic disorders may need to temporarily discontinue use of this medication. Patients with allergies to the main or other components of this drug, severely impaired liver function, or persistent unexplained elevation of liver enzymes should not take this medication. Additionally, patients with severely impaired kidney function, women who are pregnant or may become pregnant, and breastfeeding women should also not use this drug. Caution is needed for conditions such as moderate kidney impairment, hypothyroidism, a family history of muscle disorders, previous adverse reactions to other similar drugs, alcohol dependence, and certain ethnicities (Asian). This drug contains lactose, so patients with lactose intolerance should not take it. It is not recommended for patients with a history of alcohol dependence or liver disease, moderate or severe liver dysfunction. While taking this medication, regular liver function tests and muscle-related tests should be conducted, and if muscle pain, muscle weakness, fatigue, or fever occurs, you should inform healthcare personnel. This medication may interact with other drugs, so if you are currently taking other medications, be sure to inform your doctor or pharmacist. Women who are pregnant or breastfeeding should not take this medication, and fertile women should use proper contraception while taking it. The safety for children and adolescents has not been sufficiently established, so it is not recommended. Elderly patients are at higher risk for muscle side effects, so care should be taken when taking this drug. In case of an overdose, as there is no specific antidote, treatment should be symptomatic, and liver function and muscle enzyme tests should be performed. This medication should be stored out of the reach of children and transferring it to other containers is not recommended as it may affect product quality.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain of oral/ocular mucosa, shortness of breath or difficulty in breathing, asthma attacks, breathing abnormalities with cough and fever, jaundice of the skin or eyes, severe lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, significantly decreased urine output

Mild side effects

• Headache
• arthralgia
• myalgia
• edema
• increased blood bilirubin
• acneiform dermatitis
• pruritus
• dizziness
• upper respiratory tract infection
• cough

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is recommended to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. This ensures the safety of the drug's effectiveness.

Appearance

White to almost white round film-coated tablet

Package unit

Alu-Alu - 30 tablets/box [(10 tablets/Alu-Alu x 3)], bottle - 30 tablets/bottle