Medication info
Esomeprazole Magnesium Trihydrate Tablets 40 mg

Esomeprazole Magnesium Trihydrate Tablets 40 mg

Prescription medicationTablet
Ingredient · strength
Esomeprazole Magnesium Trihydrate›43.38mg / 1 tablet
Manufacturer / importer
(주)씨엠지제약
Appearance
Pink round film-coated tablets
Packaging
28 tablets (14 tablets/PTP x 2)
Approval status
Active

MFDS item code 201404652 · Approved 2014.10.10 · Insurance code 648602790

Summary

Main use
Treatment of gastroesophageal reflux disease (erosive esophagitis), eradication of Helicobacter pylori infection (duodenal ulcer), alleviation of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs, etc.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist or are untreated, an additional 4 weeks of treatment is necessary. - Maintenance therapy for the prevention of esophagitis recurrence: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis.
Children's dosage
Adolescents aged 12 and above - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist or are untreated, an additional 4 weeks of treatment is necessary. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis: Once daily,

Ingredients

Manufacturer
(주)씨엠지제약

Efficacy & effects

Treatment of gastroesophageal reflux disease (erosive esophagitis), eradication of Helicobacter pylori infection (duodenal ulcer), alleviation of gastrointestinal symptoms related to non-steroidal anti-inflammatory drugs, etc.

  • Gastroesophageal reflux disease
  • erosive esophagitis
  • esophagitis
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal symptoms
  • pain
  • discomfort
  • burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease (GERD) and erosive esophagitis and also helps prevent recurrence in patients with esophagitis. Additionally, it is effective in alleviating symptoms of gastroesophageal reflux disease without esophagitis. It is used as part of combination therapy with antibiotics for the treatment of Helicobacter pylori infection-associated duodenal ulcers and peptic ulcers, also aiding in prevention of recurrence. Furthermore, it is used in treating upper gastrointestinal symptoms and gastric ulcers caused by non-steroidal anti-inflammatory drugs, as well as preventing gastric and duodenal ulcers. This medication is also effective for the treatment of Zollinger-Ellison syndrome and for maintenance therapy to prevent rebleeding from gastric ulcers or duodenal ulcers. It is widely used for the treatment and prevention of various gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist or are untreated, an additional 4 weeks of treatment is necessary. - Maintenance therapy for the prevention of esophagitis recurrence: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis.

Children's dosage

Adolescents aged 12 and above - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks. If symptoms persist or are untreated, an additional 4 weeks of treatment is necessary. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis: Once daily,

Precautions

This medication should not be administered to certain patients. For example, patients with allergies to this medication or its components, or those with hypersensitivity to certain antibiotics, should not take it. Furthermore, women who are nursing or have a history of certain heart conditions should avoid this medication. When taking this medication, various adverse reactions may occur, necessitating caution. Gastrointestinal symptoms such as headache, abdominal pain, diarrhea, nausea, and vomiting are common, while rare cases of blood abnormalities, skin rash, and muscle pain have also been reported. In severe cases, hypersensitivity reactions such as anaphylaxis or severe skin reactions may occur, thus medical assistance should be sought if symptoms worsen. Long-term use of this medication may lead to electrolyte imbalances such as hypomagnesemia, requiring regular blood tests. Additionally, long-term use may increase the risk of fractures, thus patients with osteoporosis should be cautious. This medication can interact with other drugs, so it is important to consult a doctor, especially when taken with anticoagulants, anticonvulsants, antidepressants, or antiviral agents. Care should be taken as the effects of this medication or others may change when used in combination with certain drugs. Due to limited evidence on the safety of this medication during pregnancy, pregnant women should use it cautiously after consulting a physician. It is advisable for nursing mothers not to take this medication. In cases of overdose, there are no specific antidotes, thus it is crucial to receive appropriate treatment based on symptoms. This medication should be kept out of the reach of children and should not be transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, severe allergic reaction, jaundice, hepatitis, liver failure, encephalopathy, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), acute generalized exanthematous pustulosis, Clostridium difficile-associated diarrhea, severe edema, facial swelling, angioedema, sudden and severe headache, seizures, altered consciousness, visual disturbances,

Mild side effects

  • Leukopenia
  • thrombocytopenia
  • agranulocytosis
  • pancytopenia
  • fever
  • peripheral edema
  • hyponatremia
  • hypomagnesemia
  • insomnia
  • anxiety
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  • mental confusion
  • depression
  • aggression
  • hallucination
  • headache
  • dizziness
  • altered perception
  • drowsiness
  • taste disturbances
  • blurred vision
  • vertigo
  • bronchospasm
  • pancreatitis
  • abdominal pain
  • constipation
  • diarrhea
  • abdominal distension
  • nausea
  • vomiting
  • dry mouth
  • stomatitis
  • gastrointestinal candidiasis
  • microscopic colitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. The storage temperature should be maintained between 1 degree and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

Pink round film-coated tablets

Package unit

28 tablets (14 tablets/PTP x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.