Exvy Tablet 10/160 Milligrams

Adult dose

The recommended dosage of this medication is 1 tablet once a day, to be taken with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). This medication is to be administered to those whose blood pressure is not controlled with monotherapy of Amlodipine or Valsartan. Patients with renal impairment do not need dosage adjustment in mild to moderate cases but should not receive this medication in severe cases or those on dialysis. Hepatic impairment patients should not exceed a daily dose of 80 mg of Valsartan.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established, therefore, use of this medication is not recommended.

This medication may cause serious harm to the fetus if taken during the second and third trimesters of pregnancy; it should be discontinued immediately if pregnancy is confirmed. Patients with allergies to the active ingredients or similar class medications, women who are pregnant or breastfeeding, patients with severe kidney or liver disease, and those with a history of specific heart diseases or angioedema should avoid this medication. Patients with insufficient sodium or fluids in the body may experience hypotension, so it is crucial to verify their condition before starting the medication and monitor closely during treatment. Patients with high potassium levels or taking medications that may raise potassium levels should have their potassium levels checked frequently. Patients with reduced kidney function or those who have received a kidney transplant should be cautious as kidney function may deteriorate. If symptoms of angioedema occur, immediate discontinuation is necessary, and retaking should not occur. Patients with heart failure or post-myocardial infarction should have their kidney function periodically assessed while on the medication. The risk of hypotension, worsening kidney function, and hyperkalemia may increase when this medication is used in conjunction with other blood pressure medications, so careful monitoring of blood pressure and kidney function according to a doctor's advice is necessary. Dizziness or fatigue may occur while driving or operating machinery, so caution is advised. In case of overdose, severe hypotension or cardiac arrhythmias may occur; thus, the dosage must be strictly adhered to, and if any abnormal symptoms arise, immediate medical attention should be sought. This medication is not recommended for use in children under 18 years of age, as safety and efficacy have not been sufficiently established. In elderly patients, it can be taken at dosages similar to those used in adults, but care must be taken based on individual physical conditions.

Serious side effects

Urticaria, severe swelling (including angioedema), difficulty breathing, chest tightness, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, jaundice, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, severe generalized swelling, elevated blood pressure, hypersensitivity including serum sickness, vasculitis, renal failure, renal damage, serum sickness

Mild side effects

• Headache
• dizziness
• drowsiness
• sensory disturbances
• vertigo
• tinnitus
• tachycardia
• palpitations
• syncope
• orthostatic hypotension

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Bright yellow rectangular film-coated tablet

Package unit

28 tablets (14 tablets/PTP×2)