SynaJet ER Semi-Coated Tablets

Adult dose

The dosage for adults should be adjusted based on the patient's pain level and therapeutic response. For the initial dose, administer 2 tablets, and the subsequent dosing interval should be at least 12 hours apart. Do not exceed 8 tablets in one day. If prolonged treatment is necessary, regular monitoring should be conducted.

Patients who regularly consume more than three alcoholic beverages daily should consult their doctor or pharmacist before taking this medication, as the risk of liver damage may increase when taken with alcohol. If a rash or hypersensitivity reaction occurs while taking this medication, stop taking it immediately and inform healthcare professionals, as serious skin reactions can occur infrequently. One of the drug's components, tramadol, may increase the risk of seizures, hence patients with a history of seizures or those taking seizure-inducing medications should use it with caution. For patients with severe respiratory conditions, this drug may cause respiratory depression which can be life-threatening, and it should be administered under medical supervision. Use of this drug with alcohol or other central nervous system depressants can result in severe sedation, respiratory depression, or coma, so co-administration should be avoided. Patients with increased intracranial pressure or head injury may experience worsening symptoms when taking this medication, requiring caution. The tramadol component may cause physical and psychological dependence, so long-term use should be closely monitored for signs of dependency. Patients with liver dysfunction should consult their doctor prior to taking this medication and should avoid exceeding the recommended dosage. This drug should not be administered to children under 12 years of age and adolescents under 18 years of age following certain surgeries. Pregnant or nursing mothers should consult their doctor before taking this medication as it may affect the fetus or newborn. Drowsiness or dizziness can occur while taking this drug, so it is advised to avoid driving or operating dangerous machinery. Overdose may result in severe respiratory depression and liver damage; therefore, it is essential to adhere to the prescribed dosage and to seek medical attention immediately in the event of an overdose. Avoid combining this drug with other analgesics or products containing acetaminophen, as there may be potential drug interactions; ensure to inform healthcare professionals of any other medications being taken.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning-like headache, seizures, altered consciousness, visual disturbances, paralysis, urination problems

Mild side effects

• Weakness
• fatigue
• flushing
• rigidity
• fainting
• withdrawal symptoms
• hypertension
• worsening hypertension
• hypotension
• arrhythmia

This drug should be stored in a tightly sealed container to prevent exposure to air or moisture and should be kept at room temperature, ideally between 1°C and 30°C. Proper storage helps maintain the drug's efficacy and prevent degradation.

Appearance

Light yellow round film-coated extended-release tablet

Package unit

100 tablets/bottle, 30 tablets/bottle