Serenjal Tablet (Levocetirizine Hydrochloride)

Adult dose

Adults and children aged 6 years and older: Take 1 tablet (as levocetirizine dihydrochloride 5mg) orally once daily, regardless of meals. Adjust dosage according to age and symptoms. For patients with renal impairment, adjust the dosage based on renal function (creatinine clearance (CLCR(mL/min))). - 50 ≤ CLCR < 80: 1 tablet once daily - 30 ≤ CLCR < 50: 1 tablet once every 2 days

Child dose

Children aged 6 years and older: Take 1 tablet (as levocetirizine dihydrochloride 5mg) orally once daily, regardless of meals.

This medication should not be used in patients who are allergic to hydroxyzine or piperazine derivatives or have experienced hypersensitivity. It should also not be administered to patients with severely impaired renal function or those undergoing dialysis. It is safer for pregnant women, women who may become pregnant, and nursing mothers to avoid taking this medication. It should not be used in infants under 1 year of age and it is recommended to administer in liquid form rather than tablets for children under 6 years of age. Patients with lactose intolerance or specific genetic lactose metabolism disorders should avoid this medication due to the lactose it contains. Caution is required when administering this medication to patients with impaired renal or liver function and elderly patients as it may increase the blood concentration of the drug. This medication may cause various side effects, including drowsiness, headache, dizziness, nausea, and abdominal pain, and immediate consultation with a healthcare professional is required if symptoms are severe. Drowsiness or fatigue may occur after taking the medication, so caution is advised during activities requiring concentration such as driving or operating machinery. It is best to avoid concurrent use with alcohol or drugs that affect the central nervous system, as it may exacerbate drowsiness or decreased concentration. Patients at risk of urinary retention should use this medication with caution. Pregnant or nursing women should not take this medication, and women who may become pregnant must consult their healthcare provider before use. This medication is primarily excreted through the kidneys, so elderly patients with reduced kidney function should start at a lower dose and be closely monitored. It is not necessary to stop taking this medication prior to allergic testing, as it will not affect the test results. Symptoms such as drowsiness or agitation may occur in case of overdose, and immediate appropriate treatment should be sought at a hospital as there is no specific antidote.

Serious side effects

• Urticaria
• severe swelling (edema)
• angioedema
• anaphylactic shock
• hypertension
• pneumonia
• difficulty breathing
• urticaria.

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• somnolence
• fatigue
• dizziness
• heaviness
• excitement
• thirst

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it should be kept at room temperature, neither too high nor too low, specifically between 1 degree and 30 degrees Celsius.

Appearance

Oval film-coated tablets, white or light yellow

Package unit

30 tablets/bottle, 300 tablets/bottle