Ursa 300 mg (Ursodeoxycholic Acid)

Adult dose

For improvement of liver function in primary biliary cirrhosis, Ursodeoxycholic acid is administered orally at a dose of 300 mg three times a day with meals. For the prevention of gallstones, patients experiencing rapid weight loss should take 300 mg twice a day, and gastric cancer patients who have undergone gastric resection should take 300 mg once a day.

This medication should not be used in certain patients. For example, individuals allergic to this drug's ingredients or bile acids should not take it. Additionally, the drug is not indicated for patients with severe biliary obstruction or acute hepatitis, as it may worsen symptoms. Patients with calcified gallstones, radiolucent gallstones, or pigment gallstones should also avoid using this medication. Patients without gallbladder function or those with severe biliary diseases such as acute cholecystitis, cholangitis, biliary obstruction, or gallstone pancreatitis should not take this medication. It is not recommended for women who are pregnant or may become pregnant, breastfeeding women, and children. Caution is required for patients with impaired kidney function or inflammatory conditions of the intestines, such as peptic ulcer or Crohn's disease. This medication contains lactose, so it should not be given to patients with lactose intolerance or related genetic disorders. Patients with severe pancreatic disease or those with gallstones in the bile duct should use this drug cautiously, as should patients with severely impaired liver function. While taking this medication, regular liver function tests should be conducted, and if liver function worsens or abnormal symptoms appear, immediate consultation with a healthcare provider is necessary. Possible side effects during use may include diarrhea, nausea, vomiting, abdominal pain, headache, dizziness, skin rash; it is important to inform a doctor if symptoms worsen. This medication may interact with other drugs, so especially inform healthcare professionals if using diabetes medications, antacids, lipid-lowering agents, or drugs that affect the liver. Pregnant or breastfeeding women should ideally avoid this medication, and it is important for children or elderly patients to consult with professionals before use. In case of overdose, symptoms such as diarrhea may occur, so it is important to follow the exact dosage and immediately consult a healthcare provider if unusual symptoms arise. Finally, this medication should be kept out of reach of children and stored sealed in its original container.

Serious side effects

Interstitial pneumonia (fever, cough, difficulty breathing, abnormal chest X-ray), elevation of serum bilirubin levels, symptoms of jaundice, worsening liver function

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• constipation
• heartburn
• gastrointestinal discomfort
• itching
• rash
• general malaise

This medication may be sensitive to air or humidity, so it should be stored in a tightly closed container. The storage temperature should ideally be maintained between 1°C and 30°C at room temperature. By storing it this way, the effectiveness of the medication can be safely preserved.

Appearance

White round tablets

Package unit

30 tablets/bottle, 500 tablets/bottle, 30 tablets (10 tablets/PTP) X 3