Esvil Soft Capsule (Dexibuprofen)

Adult dose

Administer 300 mg of dexibuprofen orally, 2 to 4 times a day. However, do not exceed 1,200 mg of dexibuprofen per day.

This medication can cause gastric bleeding in individuals who regularly consume more than 3 drinks of alcohol per day, so it is essential to consult with a doctor or pharmacist. This drug may impact the cardiovascular system, potentially increasing the risk of myocardial infarction or stroke, so patients with cardiovascular conditions or risk factors should be monitored closely. Furthermore, this drug can trigger severe adverse reactions such as gastrointestinal bleeding, ulcers, and perforation, particularly posing higher risks for elderly patients or those on long-term treatment. Individuals with a history of gastrointestinal ulcers or bleeding, severe liver dysfunction, kidney dysfunction, heart failure, hypertension, etc., should not take this medication. Concurrent use with aspirin or other non-steroidal anti-inflammatory drugs may increase the risk of gastrointestinal bleeding and reduce the drug’s efficacy, so co-administration should be avoided. During treatment, it would be advisable to discontinue breastfeeding or stop the medication, as dizziness or fatigue may occur, thus caution should be exercised when driving or operating machinery. Individuals with blood disorders, liver dysfunction, kidney dysfunction, hypertension, elderly patients, and pregnant women should consult a doctor or pharmacist before taking this drug, and be aware of interactions with other medications. If symptoms such as shock, severe skin rashes, gastrointestinal bleeding, liver function abnormalities, or kidney function deterioration occur during treatment, discontinue use immediately and consult with healthcare personnel. This medication should be administered at the lowest possible dose for the shortest duration, and regular blood tests and liver and kidney function tests are important to check for abnormalities. After the 20th week of pregnancy, caution is advised as it may affect fetal kidney function, and in case of overdose, immediate medical assistance should be obtained. Finally, this medication should be stored out of reach of children, kept away from direct sunlight, and stored in a cool, dry place.

Serious side effects

• Urticaria, severe swelling (edema), chest tightness, difficulty breathing → severe allergic reaction
• Severe rash with high fever, blisters, skin detachment, pain in the mouth/eye mucosa → severe skin adverse reaction
• Shortness of breath or difficulty breathing, asthma attacks, respiratory issues coupled with cough + fever → respiratory problems
• Jaundice (yellowing of the skin or eyes), profound languor → hepatic dysfunction (jaundice)
• Sudden and very severe headache,

Mild side effects

• Dyspepsia
• abdominal bloating
• heartburn
• epigastric pain
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

Drug interactions

Do not take this medication with aspirin, other non-steroidal anti-inflammatory drugs, or high doses of methotrexate. Corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors or angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants (such as warfarin), baclofen, immunosuppressants (such as cyclosporine, tacrolimus, sirolimus),

This medication should be stored in a tightly closed container to prevent air or moisture ingress, and it is important to maintain a storage temperature between 1 to 30 degrees Celsius to preserve its efficacy and prevent degradation.

Appearance

A transparent blue oval soft capsule containing a colorless to pale blue clear liquid

Package unit

10 capsules (10 capsules/PTP*1)