Domohoron Ointment (Clobetasol Propionate)

Adult use

Apply an appropriate amount to the affected area 1-2 times a day and adjust according to symptoms. This medication is a potent corticosteroid, so do not use for more than 2 weeks continuously or apply more than 50g (50mL solution) per week.

This medication should not be used in patients with skin infections caused by bacteria, fungi, viruses, or animals. It should be avoided in individuals who are allergic to this medication or any of its ingredients. Care should also be taken in patients with perforated eardrums, external otitis, skin ulcers, or severe burns, as using this medication may delay healing. It is also advisable to refrain from use in patients with scalp infections, perioral dermatitis, acne vulgaris, rosacea, or itching in the anal and genital areas. This medication should not be used in infants under 24 months. Pregnant or breastfeeding women, children, the elderly, and patients with liver dysfunction or diabetes should use it with caution. This medication contains propylene glycol, and individuals allergic to this substance should be particularly cautious. Skin infections may develop, and if an infection worsens, use should be discontinued and appropriate treatment sought. Various skin reactions such as irritation, rash, itching, urticaria may occur, so if unusual symptoms arise, use should be stopped. Prolonged use may result in thinning of the skin, discoloration, or skin hemorrhage; therefore, long-term use should be avoided, and if symptoms appear, it is necessary to reduce the dosage or switch to another medication. Care should be taken when using this medication over large areas for extended periods or using occlusive dressings, as systemic effects may suppress hormonal function. When used around the eyes, care should be taken to avoid exposure to pressure increases, glaucoma, or cataracts. It is generally advised not to use this medication for eczema or dermatitis accompanied by skin infections, but in unavoidable cases, it should be used in conjunction with antibiotics or antifungal agents. During pregnancy, it is better not to use this medication extensively or for long periods as it may affect fetal development, and it should be used minimally only when absolutely necessary. Caution is also required during breastfeeding as this medication may be transferred through breast milk, and it is advised not to apply it directly to the nipple and breast area. Pediatric patients have a higher risk of side effects due to better absorption of the medication relative to body surface area, so caution is especially warranted, particularly in infants under 24 months. The elderly are at a higher risk for side effects, so careful monitoring is necessary when using high doses or for prolonged periods. Overuse may lead to symptoms of hormone overdose, and the dosage should be gradually reduced according to a doctor's instructions. This medication should not be applied directly to the eyes or used on areas other than for its intended purpose. After application to the hands, they should be washed thoroughly, and occlusive dressings should only be used according to a doctor’s guidance. Keep it out of reach of children and store it in the original container to prevent misuse or degradation of quality.

Serious side effects

Urticaria, skin infections (bacterial, fungal, viral infections), severe allergic reactions, skin peeling, severe rash, blisters, pain in mucous membranes of mouth/eyes, severe skin adverse reactions, difficulty breathing, respiratory issues, jaundice, yellowing of skin or eyes, liver dysfunction, severe edema, significantly reduced urine output, hypertension, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances.

Mild side effects

• Folliculitis
• pustules
• skin irritation
• pain
• fever
• burning sensation
• rash
• erythema
• flushing
• redness

This medication should be stored in a specially sealed container to prevent exposure to air or light. This helps maintain the effectiveness of the medication and prevents deterioration.

Appearance

A translucent white to pale yellow uniform ointment

Package unit

450 grams/bottle