Sodium Chloride Glucose Injection Solution (1-2)

Adult administration

For adults, administer 500–1,000mL by slow intravenous drip. The administration rate is 300–500mL per hour (75–120 drops per minute).

Child administration

For children, the administration rate should be 50–100mL per hour. Especially, in newborns and premature infants, rapid infusion (over 100mL per hour) should not be done.

This medication contains glucose, which can rapidly increase the consumption of thiamine (vitamin B1) in the body during intravenous administration. There is a risk of thiamine deficiency, so caution is required. This medication should not be used in patients with excessive fluid retention, storage dehydration, or low serum potassium levels. It should be administered carefully to patients with impaired kidney function, weak heart function, hyperosmolar dehydration, low urine output due to urinary obstruction, diabetes, and high serum chloride levels. Rapid large-volume administration of this medication can cause brain or lung edema, peripheral edema, acidosis, and excessive fluid retention in the body. The infusion rate should be adjusted slowly, especially in newborns or premature infants, as rapid administration may lead to signs of fluid overload. There is also a risk of thrombosis at the intravenous injection site, so caution is required. Blood glucose levels, serum electrolyte concentrations, and the body fluid balance status should be regularly tested and managed. During pregnancy, it should only be administered when the benefits outweigh the risks, as safety for the fetus has not been fully established. Administering this medication during delivery may cause hyperglycemia in the mother and hypoglycemia or metabolic acidosis in the newborn, necessitating careful consideration. Newborns, especially preterm or low-birth-weight infants, require close monitoring for blood sugar control as they may have difficulties. Rapid or prolonged dosing should be avoided in infants and the elderly, and extra caution should be taken to reduce circulatory burden in the elderly with weak heart or kidney function. In case of overdose, diuretics may be needed to remove excess fluid from the body. Before administration, the patient's skin and the devices used should be thoroughly disinfected, and the medication in a cold state should be warmed to body temperature before use. It should be used immediately after opening, and any unused medication should be discarded. During administration, intravenous injection should be done slowly. Additionally, to prevent air embolism, the medication containers should not be connected continuously for use.

Serious side effects

Severe edema (cerebral edema, pulmonary edema, peripheral edema)

Mild side effects

• Cerebral edema
• pulmonary edema
• peripheral edema
• acidosis
• water intoxication
• thrombosis

This medication should be stored in a sealed container to protect it from air and moisture. The storage temperature should be maintained at room temperature between 1 to 30 degrees Celsius.

Appearance

This medication is a colorless, transparent liquid filled in a glass or plastic container with a slight salty and sweet taste.

Package unit

500mL/pack