Medication info
Hyun's Amlodipine Tablet 5mg (Amlodipine Besilate)

Hyun's Amlodipine Tablet 5mg (Amlodipine Besilate)

Prescription medicationTablet경구
Ingredient · strength
Amlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
(주)휴온스
Appearance
White octagonal tablets
Packaging
Bottle packaging - 30 tablets/bottle, bottle packaging - 300 tablets/bottle
Approval status
Active

MFDS item code 201500483 · Approved 2015.01.30 · Insurance code 670607180

Summary

Main use
Improvement of myocardium ischemia due to hypertension and coronary artery disease (stable and variant angina) and reduction of the risk of hospitalization due to angina and risk of vascular revascularization.
Who takes it
Adults
Adult dose
Administer 5mg orally once daily as amlodipine, and may increase to a maximum of 10mg per day according to the patient's response. Adjust as appropriate based on age and symptoms.

Ingredients

Manufacturer
(주)휴온스

Efficacy & effects

Improvement of myocardium ischemia due to hypertension and coronary artery disease (stable and variant angina) and reduction of the risk of hospitalization due to angina and risk of vascular revascularization.

  • Hypertension
  • fixed obstruction of the coronary artery
  • vascular spasm in the coronary circulation
  • vasoconstriction
  • myocardium ischemia
  • angina
View approved original text

This medication is used to treat myocardium ischemia caused by stable angina due to hypertension and fixed obstruction of the coronary artery, or variant angina due to vascular spasm and vasoconstriction. Additionally, it helps to reduce the risk of hospitalization due to angina in patients with coronary artery disease confirmed by recent angiography, with no heart failure and an ejection fraction of over 40%. This medication also reduces the risk of vascular revascularization of coronary arteries, thus supporting health management. Therefore, it is effectively used for the treatment of vascular-related heart diseases and prevention of complications.

How to take

Adult dose

Administer 5mg orally once daily as amlodipine, and may increase to a maximum of 10mg per day according to the patient's response. Adjust as appropriate based on age and symptoms.

Precautions

This medication should not be administered to specific patients. For instance, patients who are allergic to this medication or similar kinds of drugs, nursing women, patients with severe liver dysfunction, patients with severe aortic stenosis, and patients in shock should not use this medication. Furthermore, this medication should be used cautiously in patients with very low blood pressure, patients requiring kidney dialysis, elderly patients, and women who are pregnant or may become pregnant. Taking this medication may cause side effects such as facial flushing, fatigue, swelling of the hands and feet, palpitations, dizziness, headache, drowsiness, abdominal pain, nausea. Rarely, various adverse reactions such as blood pressure drop, skin rash, allergic reactions, muscle pain, liver dysfunction may occur, so caution is necessary. In patients with heart failure, this medication may exacerbate pulmonary edema, therefore it should be used with caution, and in patients with liver impairment, the effect of this medication may last longer, requiring dose adjustments. This medication is not suitable for acute heart issues as its effects appear gradually. This medication can interact with several other drugs, so if you are taking any other medications, you must consult with healthcare professionals. Particularly, it is advisable to avoid taking it with grapefruit juice since it can excessively enhance the drug's effects. The safety of this medication has not been established in pregnant or nursing women, thus it is recommended to avoid use except in special cases. For children, its use is recommended only for those 6 years and older, as safety and efficacy have not been confirmed for younger children. In cases of overdose, severe drops in blood pressure and irregular heartbeats may occur, so it is essential to visit a medical institution immediately, and in severe cases, emergency treatment may be required. While taking this medication, driving or operating machinery is generally safe; however, caution should be exercised if dizziness or drowsiness occurs.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • severe swelling (edema)
  • severe allergic reactions
  • toxic epidermal necrolysis
  • jaundice
  • liver abnormalities
  • severe skin reaction
  • severe edema or urinary abnormalities
  • angioedema

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
Show 25 more
  • lethargy
  • weight gain/loss
  • hypotension
  • vasculitis
  • tension
  • sensory loss/sensation abnormalities
  • peripheral neuropathy
  • syncope
  • taste disturbance
  • tremors
  • extrapyramidal disorder
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • indigestion
  • gingival hypertrophy
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps
  • myalgia
  • leukopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air ingress, and it is advisable to keep the temperature between 1 and 30 degrees Celsius at room temperature. By storing it this way, the medication's effectiveness and safety can be maintained.

Appearance and packaging

Appearance

White octagonal tablets

Package unit

Bottle packaging - 30 tablets/bottle, bottle packaging - 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.