Perfluorinated compounds promote thyroid cancer metastasis… Beware of these commonly used substances.

Even extremely low concentrations of perfluorinated compounds (PFACs) can worsen thyroid cancer metastasis. Research results have been published that say that.

Perfluorinated compounds are a group of approximately 4,700 chemical compounds.

 

These perfluorinated compounds, a combination of carbon and fluorine, are heat-resistant and water- and oil-repellent, making them useful in a variety of consumer products, including frying pan coatings, fast-food packaging, and waterproof clothing. These perfluorinated compounds can permeate consumer products, soil, and groundwater, ultimately reaching the human body.

 

The half-life of the most representative perfluorinated compounds, perfluorooctanoic acid and perfluorooctanesulfonic acid, in the body is known to be 3.8 to 5.4 years. If accumulated in the body, it can cause immune system diseases such as liver damage and hormonal disruption, as well as affect the fetus through the placenta. It is known that it can give .

A research team at the Korea Institute of Health and Social Affairs conducted a study to determine the effects of perfluorinated compounds on thyroid cancer. First, they developed organoids using thyroid cancer cell lines. Organoids are artificially created tissue-like structures by culturing human-derived cells. The team exposed thyroid cancer organoids to 10 μM (micromolar), a non-cytotoxic level, for 21 days and then observed the metastasis of the cancer.

 

As a result, "epithelial-mesenchymal transition," a biomarker (a biological indicator used to diagnose the extent of disease progression) indicating cancer metastasis potential, was activated. Epithelial-mesenchymal transition is the process by which epithelial cells transform into mesenchymal cells capable of metastasis. Furthermore, increased expression of the Ki-67 protein, which is produced when cells divide and proliferate, was observed.

 

“This is the first study to elucidate the mechanism by which perfluorinated compounds affect cancer metastasis using thyroid cancer organoids,” said Senior Researcher Yoo Min-hee. “This will contribute to establishing a clear regulation and management system for perfluorinated compounds.”

 

Some perfluorinated compounds have been designated as carcinogens by the International Agency for Research on Cancer, a division of the World Health Organization (WHO), due to their potential to cause diseases such as thyroid, kidney, and testicular cancer. Consequently, countries around the world are pursuing regulations.

 

one side, Thyroid cancer is sometimes called turtle cancer because the cancer cells grow slowly. But it is rare In some patients, thyroid cancer grows rapidly and metastasizes to the lymph nodes and lungs. 

This also lowers survival rates. Specifically, if thyroid cancer has lymph node metastasis, the 10-year survival rate is only about 45%. The problem is that there are no reliable predictors of thyroid cancer metastasis.

 

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My friend also had thyroid cancer.

This is my first time hearing about 'Turtle Front'

 

According to my friend

They say stress is the biggest thing

In my friend's case, after he got thyroid cancer

I think I just quit the company.

 

I was a banker, and I was under a lot of stress.

Well, my job isn't the problem,

 

In particular, it seems that cancer is also caused by stress.

 

 

When I get food to go, I rarely take the dishes with me.

The packaging is also a problem.