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Loto Zypai is a well-known eye drop in Japan, as you know. A friend brought it back from Japan and gave it to me as a gift, and I've been using it ever since. The cool, refreshing sensation is the best. For first-time users, it may feel a bit刺激 (刺激 can mean刺激 or刺激感, but in this context, it likely refers to a刺激 or刺激 sensation), but you'll get used to it quickly. Since it contains a variety of ingredients, please consult with a pharmacist before trying it for the first time. It is said to be a complex formulation, including antihistamines and other components. Also, it is not recommended to use while wearing contact lenses. It should be used no more than six times a day. I recommend this traditional Japanese product.