몇몇 연구에서 효과를 입증했지만 관찰 연구만으로 비타민D 보충과 당뇨병의 인과관계를 확립할 수 없으며 효과를 내기 위한 정확한 용량을 정의하기 어렵다. 게다가 일부 임상연구에서 효과가 부풀려졌다는 결과도 나오면서 비타민D 보충에 대한 논란이 이어지고 있는 상황이다.비타민D가 논란이 많군요~
A study has shown that even long-term high-dose vitamin D intake by healthy adults has no significant effect on reducing the risk of developing diabetes.
Vitamin D is known to improve insulin resistance, help regulate blood sugar levels, and reduce the risk of developing diabetes. According to a study published in the Journal of American Clinical Nutrition, people with low vitamin D levels had a higher risk of developing diabetes compared to those with normal levels. Research findings also support that supplementing vitamin D in high-risk groups for diabetes can improve insulin sensitivity.
Although some studies have demonstrated effectiveness, observational studies alone cannot establish a causal relationship between vitamin D supplementation and diabetes, and it is difficult to define the precise dosage needed for effectiveness. Moreover, some clinical studies have shown inflated results, leading to ongoing controversy over vitamin D supplementation.
Amid ongoing debates about whether vitamin D supplementation is effective in preventing diabetes, a research team from Eastern Finland University conducted a study to demonstrate the effects of long-term high-dose vitamin D intake.
The research team conducted a follow-up study over approximately five years on 2,495 men aged 60 and over and 2,495 women aged 65, all without glucose metabolism disorders. Participants were randomly assigned to three groups: daily vitamin D3 40μg (1600IU), daily vitamin D3 80μg (3200IU), or a placebo group. The research team utilized national health registry data to collect information on participants' lifestyles, nutrition, diseases, and risk factors, and they collected blood samples for analysis.
Over five years, 105 people developed diabetes. The number of diabetes cases in each group was ▲40 μg/day vitamin D3 group with 31 people, ▲80 μg/day vitamin D3 group with 36 people, and the placebo group with 38 people, with no statistically significant differences among the groups.
During the first two years, the effects of vitamin D on blood glucose, insulin levels, body mass index, and waist circumference were investigated, but no differences were found between the groups.
The research team analyzed that factors such as the research subjects and the limitations of high-dose vitamin D had an impact.
The research team explained that vitamin D may be effective for high-risk groups such as those in the pre-diabetes stage, but its effects may not be as evident in healthy individuals.
The research team stated, "Even if vitamin D has a beneficial effect on blood sugar levels, taking excessive amounts does not double the effect."
He said that because many other factors such as genetic factors, eating habits, and exercise also influence the development of diabetes, relying solely on vitamin D may not be sufficient for effective prevention.
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Diabetes management is related to eating habits.
It seems that prevention through exercise comes first.
Have you come to learn about the relationship with vitamin D?