What is lupus and why is it important?

Lupus causes inflammation in many parts of the body. autoimmune diseases are you.
The problem is that the symptoms are not fixed to one thing.
Like fatigue, erythema, joint pain, and stomatitis It appears completely differently for each person He was nicknamed 'The Face of a Thousand Faces'.

 

• Red spots first appeared on my face several years ago.

• I went to the hospital because of severe fatigue.

• In some cases, it can even lead to mouth inflammation and joint pain.

Here's why it's easy to miss early symptoms.

 

Why is it dangerous to ignore the early symptoms?

Lupus is Early treatment is important It is introduced as a disease.
At first, it is easy to dismiss it as simple fatigue, but if diagnosis is delayed, the inflammation can worsen.

In fact, there were cases where it was initially dismissed as mild, but upon later examination, the condition became serious and required high-dose steroid and cyclophosphamide treatment.

Fortunately, proteinuria decreased rapidly after aggressive treatment, but it is also noted that not all patients respond the same way.

Because lupus is difficult to predict when it will be active and when it will relapse, Early response is crucial You can understand it as a message.

 

Lupus Treatment: Why Are Chemotherapy Drugs Being Adventured?

For the treatment of lupus

• Steroids (basic treatment)

• immunosuppressants (some of which are known anticancer drugs)

• Drugs such as hydroxychloroquine and aspirin
  can be used together.

Here, the drug that sounds like an 'anticancer drug' is actually Drugs used to suppress immunity Yes.
As a representative example, ‘Benista’ is mentioned. B-cell activation inhibitor It is known to be helpful in reducing steroid dosage.

but It doesn't work the same for everyone. , research is underway to predict who will respond to which drug.

 

When Conventional Treatments Don't Work: The Role of Biologics

Even with the use of steroids and immunosuppressants, pain, fatigue, and skin problems may persist.

I had a hard time with joint pain and hair loss, There are also cases where symptoms improved after treatment with biological agents and steroids could be discontinued.

 

📌 How biological agents work

• The signal required for B cells to produce antibodies block

• Stimuli that bind to B cell surface receptors Stop it Control excessive autoantibody production

• As a result, it may help stabilize lupus activity.

In the past, the cost burden was high due to limited insurance coverage, but now there are cases where treatment is maintained consistently.

 

How much has the survival rate changed for lupus patients?

• 50 years ago : 5-year survival rate less than 50%

• recent : 5 year survival rate 97~98% , the 10-year survival rate also improved significantly.

Thanks to active drug treatment and new drugs Overall quality of life and prognosis improved. is the message.

 

🔍 Where will treatment go in the future?

The biggest challenge is The fact that each patient responds very differently to medication are you.
That's why medical professionals say they value research that can help them determine in advance who will respond well to which treatment.

 

Current research direction

• After using the medicine for a certain period of time

• By observing changes in specific cells

• Subsequent treatment response prediction Developing a method to do

As this technology advances, it could be of great help in developing personalized treatment strategies.

 

organize

• Lupus causes fatigue, erythema, joint pain, and stomatitis. The symptoms are diverse, making diagnosis difficult. has the following characteristics:

• Early detection and treatment are important, and some cases may require strong immunosuppressive therapy.

• Steroids, immunosuppressants, and biological agents may be used, and drug responses vary from patient to patient.

• Survival rates have improved significantly compared to the past, and will continue to do so. Response prediction technology This is an important research direction.